Global Lysosomal Acid Lipase (LAL) Deficiency Treatment Market : Industrial Analysis, Growth, Segmen
Lysosomal Acid Lipase deficiency (LAL-D) is an inherited, ultra-rare, autosomal recessive Lysosomal storage disease. The deficiency is caused due to mutations in the LAL gene. These alterations in the gene, prevent it from breaking down the cholesteryl esters and triglycerides. As a result, there is accumulation of lipids in the liver, spleen and the walls of blood vessels. The deficiency of LAL enzyme causes the autosomal recessive disorders- Wolman Disease (WD) and Cholesteryl Ester Storage Disease (CESD).